Denosyl for Large Dogs

Antioxidant liver support therapy.

PAW Denosyl is sold as adjunctive treatment for liver disease or dysfunction, such as the following: Chronic hepatitis Hepatic lipidosis Cholangiohepatitis Paracetamol toxicity Corticosteroid use (Note: does not prevent corticosteroid induced hepatic vacuolar change) Other acute or chronic hepatopathies, including hepatotoxins and neoplasia

Denosy contains S-adenosylmethionine (SAMe), a precursor to the potent antioxidant Glutathione that protects hepatic cells from toxins and death. It is recommended to improve hepatic glutathione levels in patients to help maintain and protect liver function. Denosyl may also be used in other areas of tissue oxidative injury caused by certain toxins or drugs which are related to reduced glutathione concentrations.4 Denosy®, however, goes beyond increasing glutathione levels and has been shown to protect liver cells from cell death and may be useful in cell regeneration. Aids in liver detoxification mechanisms in dogs and cats May be used in other areas of tissue oxidative injury and blood cell fragility caused by certain drugs May protect against negative effects on the liver caused by some medications Very high safety profile Also supports healthy brain function in senior dogs

Dosage & Administration

Absorption of Denosyl is decreased when it is given with a meal. For optimal absorption, administer Denosyl at least one hour before feeding your pet. For owners who find it difficult to administer tablets to their pets, Denosyl tablet(s) may be disguised in a small bite of moist food. It is not necessary to withhold water from your pet when giving Denosyl. In cats, tablets or capsules can 'stick' in the throat instead of passing into the stomach. Therefore, cat owners should gently administer a small amount of water immediately following tablet administration to aid swallowing. Denosyl tablets should not be broken as the enteric coating of the Denosyl tablet protects the active ingredient from destruction while in the stomach. The number of tablets can be gradually reduced or increased at any time depending on the pet's needs. When increasing or decreasing the dose, adjustments should be done in full tablet increments. Many pets are maintained long-term on every-other-day or every-third-day administration.

Body Weight (kg) Denosyl Cats S Dogs Denosyl M Dogs Denosyl L Dogs up to 5.9kg 1 tablet daily - - 6 to 15.9kg - 1 tab daily - 16 to 29.9kg (Opt 1) - 2 tabs daily - 16 to 29.9kg (Opt 2) - - 1 tab daily 30 to 54.9kg - - 2 tabs daily over 55kg - - 3 tabs daily

Active Ingredient Contains the active ingredient S-adenosylmethionine (SAMe) in an enteric coated tablet.

For more information and option to buy link to: www.petmedz.co.nz